Dan Li Selected Research

Parkinson Disease (Parkinson's Disease)

3/2024	Phosphorylation and O-GlcNAcylation at the same α-synuclein site generate distinct fibril structures.
1/2024	A cell therapy approach based on iPSC-derived midbrain organoids for the restoration of motor function in a Parkinson's disease mouse model.
1/2024	Inhibition of GluN2D-Containing NMDA Receptors Protects Dopaminergic Neurons against 6-OHDA-Induced Neurotoxicity via Activating ERK/NRF2/HO-1 Signaling.
1/2023	Structural Insights of Fe3+ Induced α-synuclein Fibrillation in Parkinson's Disease.
1/2023	Associations between variants in levodopa metabolic pathway genes and levodopa-induced dyskinesia in Parkinson's disease.
1/2023	Quantitative Transcranial Sonography Evaluation of Substantia Nigra Hyperechogenicity Is Useful for Predicting Levodopa-Induced Dyskinesia in Parkinson Disease.
1/2023	Conformational change of α-synuclein fibrils in cerebrospinal fluid from different clinical phases of Parkinson's disease.
2/2022	Cellular and animal models to investigate pathogenesis of amyloid aggregation in neurodegenerative diseases.
1/2022	Generic amyloid fibrillation of TMEM106B in patient with Parkinson's disease dementia and normal elders.
1/2022	Induction of Parkinsonian-Like Changes via Targeted Downregulation of Astrocytic Glutamate Transporter GLT-1 in the Striatum.

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Dan Li Research Topics

Disease

691	Neoplasms (Cancer) 06/2024 - 04/2002
156	Inflammation (Inflammations) 05/2024 - 11/2006
146	Infections 05/2024 - 01/2003
103	Neoplasm Metastasis (Metastasis) 04/2024 - 05/2009
69	Carcinogenesis 05/2024 - 01/2008
63	Hepatocellular Carcinoma (Hepatoma) 05/2024 - 01/2003
60	Breast Neoplasms (Breast Cancer) 05/2024 - 03/2009
53	Stomach Neoplasms (Stomach Cancer) 12/2023 - 01/2008
46	Fibrosis (Cirrhosis) 04/2024 - 03/2003
46	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2024 - 07/2009
45	COVID-19 04/2024 - 01/2020
44	Lung Neoplasms (Lung Cancer) 06/2024 - 06/2010
39	Colorectal Neoplasms (Colorectal Cancer) 01/2024 - 04/2005
36	Cardiovascular Diseases (Cardiovascular Disease) 02/2024 - 12/2009
33	Atherosclerosis 03/2024 - 11/2008
32	Hypertension (High Blood Pressure) 12/2023 - 09/2006
31	Hypoxia (Hypoxemia) 04/2024 - 08/2007
31	Parkinson Disease (Parkinson's Disease) 03/2024 - 05/2010
30	Prostatic Neoplasms (Prostate Cancer) 03/2024 - 10/2005
28	Neurodegenerative Diseases (Neurodegenerative Disease) 01/2024 - 10/2012
27	Pancreatic Neoplasms (Pancreatic Cancer) 04/2024 - 01/2012
27	Cataract (Cataracts) 01/2024 - 01/2015
26	Uterine Cervical Neoplasms (Cancer of the Cervix) 04/2024 - 01/2007
26	Insulin Resistance 12/2023 - 01/2012
26	Reperfusion Injury 12/2023 - 01/2009
26	Adenocarcinoma 08/2023 - 01/2007
25	Pain (Aches) 05/2024 - 06/2009
23	Carcinoma (Carcinomatosis) 11/2023 - 12/2003
22	Alzheimer Disease (Alzheimer's Disease) 10/2024 - 04/2005
22	Liver Neoplasms (Liver Cancer) 02/2024 - 01/2003
22	Leukemia 01/2023 - 04/2006
21	Wounds and Injuries (Trauma) 05/2024 - 01/2008
21	Sepsis (Septicemia) 02/2024 - 05/2010
21	Neuroblastoma 10/2023 - 08/2007
20	Heart Failure 03/2024 - 09/2012
20	Ovarian Neoplasms (Ovarian Cancer) 03/2024 - 04/2002
20	Body Weight (Weight, Body) 06/2023 - 02/2008
19	Myocardial Infarction 04/2024 - 01/2013
19	Glioma (Gliomas) 01/2023 - 08/2006
18	Melanoma (Melanoma, Malignant) 04/2024 - 01/2007
18	Hemorrhage 02/2024 - 09/2011
17	Hematologic Neoplasms (Hematological Malignancy) 04/2024 - 02/2003
17	Colonic Neoplasms (Colon Cancer) 10/2023 - 04/2005
16	Ischemia 02/2024 - 01/2006
16	Adenocarcinoma of Lung 01/2024 - 02/2015
15	Necrosis 05/2024 - 11/2009

Drug/Important Bio-Agent (IBA)

240	Proteins (Proteins, Gene)FDA Link 04/2024 - 01/2003
106	Biomarkers (Surrogate Marker)IBA 04/2024 - 09/2008
69	CytokinesIBA 05/2024 - 01/2003
66	Messenger RNA (mRNA)IBA 01/2024 - 09/2006
63	MicroRNAs (MicroRNA)IBA 01/2024 - 03/2009
55	EnzymesIBA 04/2024 - 01/2003
48	Glucose (Dextrose)FDA LinkGeneric 02/2024 - 04/2005
45	Therapeutic UsesIBA 12/2023 - 02/2008
44	VaccinesIBA 04/2024 - 11/2007
43	Long Noncoding RNAIBA 10/2023 - 01/2014
42	DNA (Deoxyribonucleic Acid)IBA 12/2023 - 04/2002
40	Peptides (Polypeptides)IBA 02/2024 - 11/2007
38	LipidsIBA 04/2024 - 03/2010
34	RNA (Ribonucleic Acid)IBA 04/2024 - 08/2014
34	Small Interfering RNA (siRNA)IBA 01/2022 - 06/2010
32	Interleukin-6 (Interleukin 6)IBA 02/2024 - 01/2007
31	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2024 - 02/2010
30	Amyloid (Amyloid Fibrils)IBA 03/2024 - 01/2015
30	LigandsIBA 07/2023 - 06/2012
28	Transcription Factors (Transcription Factor)IBA 05/2024 - 10/2005
28	AntioxidantsIBA 11/2023 - 11/2008
27	Anti-Bacterial Agents (Antibiotics)IBA 01/2024 - 08/2007
27	AntigensIBA 12/2023 - 11/2009
26	LipopolysaccharidesIBA 03/2023 - 12/2014
25	AntibodiesIBA 02/2024 - 07/2013
22	Phosphotransferases (Kinase)IBA 05/2024 - 06/2009
22	Doxorubicin (Adriamycin)FDA LinkGeneric 02/2024 - 06/2012
22	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 02/2024 - 11/2007
22	Indicators and Reagents (Reagents)IBA 11/2023 - 03/2013
21	Chimeric Antigen ReceptorsIBA 01/2024 - 01/2016
21	Matrix Metalloproteinases (MMPs)IBA 12/2023 - 05/2009
21	Cisplatin (Platino)FDA LinkGeneric 01/2023 - 04/2002
20	Monoclonal AntibodiesIBA 01/2024 - 06/2007
20	Paclitaxel (Taxol)FDA LinkGeneric 12/2023 - 06/2009
20	CholesterolIBA 10/2023 - 11/2008
19	Antiviral Agents (Antivirals)IBA 01/2024 - 06/2009
19	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 06/2023 - 04/2002
18	Androgen Receptors (Androgen Receptor)IBA 03/2024 - 04/2013
17	SynucleinsIBA 03/2024 - 01/2018
17	ProdrugsIBA 12/2022 - 01/2012
16	AcidsIBA 04/2024 - 10/2011
16	CollagenIBA 01/2024 - 12/2005
16	Circular RNAIBA 11/2023 - 01/2019
16	ChemokinesIBA 06/2023 - 10/2010
16	CateninsIBA 01/2023 - 08/2013
16	GoldIBA 06/2022 - 03/2011
15	AlbuminsIBA 04/2024 - 10/2010

Therapy/Procedure

321	Therapeutics 05/2024 - 01/2003
81	Drug Therapy (Chemotherapy) 05/2024 - 04/2002
74	Immunotherapy 05/2024 - 11/2007
37	Radiotherapy 04/2024 - 01/2012
18	Lasers (Laser) 01/2024 - 01/2008
17	Precision Medicine 11/2023 - 01/2014
15	Chinese Traditional Medicine (Traditional Chinese Medicine) 05/2024 - 01/2013